Article
Mitsugumin 53-mediated maintenance of K+ currents in cardiac myocytes.
Channels (Austin, Tex.) - 1 Jan 2000
Masumiya Haruko, Asaumi Yasuhide, Nishi Miyuki, Minamisawa Susumu, Adachi-Akahane Satomi, Yoshida Morikatsu, Kangawa Kenji, Ito Kenta, Kagaya Yutaka, Yanagisawa Teruyuki, Yamazaki Tetsuo, Ma Jianjie, Takeshima Hiroshi
Abstract excerpt
Mitsugumin 53 (MG53) is a muscle-specific RBCC/TRIM family member predominantly localized on small vesicles underneath the plasma membrane. Upon cell-surface lesion MG53 recruits the vesicles to the repair site in an oxidation-dependent manner and MG53-knockout mice develop progressive myopathy a...
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