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Article

Membrane repair defects in muscular dystrophy are linked to altered interaction between MG53, caveolin-3, and dysferlin.

The Journal of biological chemistry - 5 Jun 2009

Cai Chuanxi, Weisleder Noah, Ko Jae-Kyun, Komazaki Shinji, Sunada Yoshihide, Nishi Miyuki, Takeshima Hiroshi, Ma Jianjie

Abstract excerpt

Defective membrane repair can contribute to the progression of muscular dystrophy. Although mutations in caveolin-3 (Cav3) and dysferlin are linked to muscular dystrophy in human patients, the molecular mechanism underlying the functional interplay between Cav3 and dysferlin in membrane repair of muscle physiology and disease has not been fully resolved. We recently discovered that mitsugumin 53 (MG53), a...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 19380584
DOI: 10.1074/jbc.M109.009589
PMCID: PMC2708885

Genes

TRIM72

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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