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MicroRNA-124-3p Plays a Crucial Role in Cleft Palate Induced by Retinoic Acid

9 Jun 2021

Abstract excerpt

Cleft lip with/without cleft palate (CL/P) is one of the most common congenital birth defects, showing the complexity of both genetic and environmental contributions [e.g., maternal exposure to alcohol, cigarette, and retinoic acid (RA)] in humans. Recent studies suggest that epigenetic factors, including microRNAs (miRs), are altered by various environmental factors. In this study, to investigate whether and how...

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PMID: 34178974
DOI: 10.3389/fcell.2021.621045

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