[Dynamic expression of wnt and fibroblast growth factor ligands in cleft palate induced by retinoic acid].

Abstract excerpt

OBJECTIVE: To screen the wnt and fibroblast growth factor (FGF) ligands involved in palatogenesis and cleft palate, and to study the dynamic expression of them in the different stages of palatal development and cleft palate formation. METHODS: Mouse model of retinoic acid (RA)-induced cleft palate was set up. At embryo day (ED) 14.5, the palatal tissues of RA-treated group and wild type were collected and...

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