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Article

Identification of 2 loci associated with development of myxomatous mitral valve disease in Cavalier King Charles Spaniels.

The Journal of heredity - 1 Jan 2000

Madsen Majbritt Busk, Olsen Lisbeth Høier, Häggström Jens, Höglund Katja, Ljungvall Ingrid, Falk Torkel, Wess Gerhard, Stephenson Hannah, Dukes-McEwan Joanna, Chetboul Valérie, Gouni Vassiliki, Proschowsky Helle Friis, Cirera Susanna, Karlskov-Mortensen Peter, Fredholm Merete

Abstract excerpt

Myxomatous mitral valve disease (MMVD) is the most common heart disease in dogs. It is characterized by chronic progressive degenerative lesions of the mitral valve. The valve leaflets become thickened and prolapse into the left atrium resulting in mitral regurgitation (MR). MMVD is most prevalent in small to medium sized dog breeds, Cavalier King Charles Spaniels (CKCS) in particular. The onset of MMVD is highly...

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PMID: 21846748
DOI: 10.1093/jhered/esr041

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