Article

Identification of lung adenocarcinoma subtypes and a prognostic signature based on activity changes of the hallmark and immunologic gene sets

2022-11-18

Abstract excerpt

<title>Abstract</title> <p><bold>Background: </bold>Lung adenocarcinoma (LUAD) has a complex tumor heterogeneity. This study aimed to identify LUAD subtypes and build a reliable prognostic signature based on the activity changes of the hallmark and immunologic gene sets. <bold>Methods: </bold>Changes in the activities of the hallmark and immunologic gene sets were analyzed based on The Cancer Genome Atlas (TCGA)-...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 35196784-234c-5d2b-8124-2b4833976dff
DOI: 10.21203/rs.3.rs-2248895/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Identification of lung adenocarcinoma subtypes and a prognostic signature based on activity changes of the hallmark and immunologic gene setsDOI 10.21203/rs.3.rs-2248895/v1Read

Identification of an immune signature predicting prognosis risk of patients in lung adenocarcinomaSemantic proximity Read

Exploration of the prognostic signature reflecting tumor microenvironment of lung adenocarcinoma based on immunologically relevant genesSemantic proximity Read

Comprehensive analysis of prognostic immune-related genes in the tumor microenvironment of lung adenocarcinomaSemantic proximity Read

Identification of lung adenocarcinoma subtypes and predictive signature for prognosis, immune features, and immunotherapy based on immune checkpoint genesSemantic proximity Read

A new immune signature for survival prediction and immune checkpoint molecules in lung adenocarcinoma.Semantic proximity Read

Identification of prognostic candidate signatures by systematically revealing transcriptome characteristics in lung adenocarcinoma with differing tumor microenvironment immune phenotypes.Semantic proximity Read

Seven-gene biomarkers reveal prognostic and immune signatures in lung adenocarcinomaSemantic proximity Read

Combination of tumor mutation burden and immune infiltrates for the prognosis of lung adenocarcinoma.Semantic proximity Read

CD8+ T Cell-Associated Gene Signature Correlates With Prognosis Risk and Immunotherapy Response in Patients With Lung AdenocarcinomaSemantic proximity Read

Identification of an immune-related genes signature in lung adenocarcinoma to predict survival and response to immune checkpoint inhibitorsSemantic proximity Read

Identification and Validation of Immune-Related LncRNA Prognostic Signature for Lung AdenocarcinomaSemantic proximity Read

Construction of a novel prognostic model for evaluation of immune infiltration and immunotherapy in lung adenocarcinomaSemantic proximity Read