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Exploring and modelling colon cancer inter-tumour heterogeneity: opportunities and challenges

9 Jul 2020

Abstract excerpt

Colon cancer inter-tumour heterogeneity is installed on multiple levels, ranging from (epi)genetic driver events to signalling pathway rewiring reflected by differential gene expression patterns. Although the existence of heterogeneity in colon cancer has been recognised for a longer period of time, it is sparingly incorporated as a determining factor in current clinical practice. Here we describe how...

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PMID: 32647253
DOI: 10.1038/s41389-020-00250-6

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