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Multiregional transcriptomics identifies congruent consensus subtypes with prognostic value beyond tumor heterogeneity of colorectal cancer

21 May 2024

Abstract excerpt

Intra-tumor heterogeneity compromises the clinical value of transcriptomic classifications of colorectal cancer. We investigated the prognostic effect of transcriptomic heterogeneity and the potential for classifications less vulnerable to heterogeneity in a single-hospital series of 1093 tumor samples from 692 patients, including multiregional samples from 98 primary tumors and 35 primary-metastasis sets. We...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 38773143
DOI: 10.1038/s41467-024-48706-2

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