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Article

Incidence and prognosis of clonal hematopoiesis in patients with chronic idiopathic neutropenia.

Blood - 7 Oct 2021

Tsaknakis Grigorios, Gallì Anna, Papadakis Stavros, Kanellou Peggy, Elena Chiara, Todisco Gabriele, Bono Elisa, Rizzo Ettore, Molteni Elisabetta, Fragiadaki Irene, Mavroudi Irene, Pontikoglou Charalampos, Batas Anastasios, Maxouri Stella, Linardaki Emmanouela, Tavernarakis Nektarios, Malcovati Luca, Papadaki Helen A

Abstract excerpt

The incidence and prognosis of clonal hematopoiesis in patients with isolated neutropenia among patients with idiopathic cytopenia of undetermined significance (ICUS), known as ICUS-N or chronic idiopathic neutropenia (CIN) patients, is poorly defined. The current study sought to investigate the frequency and clinical significance of mutations of genes implicated in myeloid malignancies using next-generation...

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Identifiers

PMID: 34166485
DOI: 10.1182/blood.2021010815

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