Article
Molecular characteristics of primary pulmonary lymphoepithelioma-like carcinoma based on integrated genomic analyses.
Signal transduction and targeted therapy - 8 Jan 2021
Chen Bojiang, Zhang Yu, Dai Sisi, Zhou Ping, Luo Wenxin, Wang Zhoufeng, Chen Xuping, Cheng Peng, Zheng Guoya, Ren Jing, Yang Xiaodong, Li Weimin
Abstract excerpt
Primary pulmonary lymphoepithelioma-like carcinoma (pLELC) is a rare non-small cell lung cancer (NSCLC) subtype. Clinical features have been described in our previous report, but molecular characteristics remain unclear. Herein, pLELC genomic features were explored. Among 41,574 lung cancers, 128 pLELCs and 162 non-pLELC NSCLCs were enrolled. Programmed cell death ligand 1 (PD-L1) and protein 53 (p53) expression...
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