Article
The association between genetic variation rs2292832 and the processing efficiency of pre-mir-149 affects the risk of breast cancer.
Molecular biology reports - 1 Jan 2023
Fakhrezare Farzaneh, Ebrahimi Seyed Omar, Reiisi Somayeh
Abstract excerpt
BACKGROUND: microRNAs (miRNAs) play key roles in regulating cancer development, including breast cancer. Variation in miRNA genes can associate with the risk of cancer by alterations in the miRNA's processing and maturation. Therefore, human blood samples and breast cancer cell line (MCF7) were analyzed to study any possible association between the genetic variant (rs2292832) in the miR-149 precursor and breast...
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