Article
miR-149 rs2292832 C allele enhances the cytotoxic effect of temozolomide against glioma cells.
Neuroreport - 8 Apr 2020
Xu Binchu, Luo Xinlin, Ning Xinjie, Luo Juncheng, Guo Jian, Liu Qingchang, Ling Gengqiang
Abstract excerpt
Glioma is a common cancer that affects people worldwide with high morbidity and mortality. Human miR-149 rs2292832 C/T polymorphism and miR-149-5p expressions have been documented to play important roles in various type of cancers. This study aims to assess the impact of miR-149 rs2292832 C/T polymorphism and miR-149-5p expressions in cytotoxic effect of temozolomide against glioma cells. A total of 137 cases of...
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