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Article

Common nonsynonymous substitutions in SLCO1B1 predispose to statin intolerance in routinely treated individuals with type 2 diabetes: a go-DARTS study.

Clinical pharmacology and therapeutics - 1 Feb 2011

Donnelly L A, Doney A S F, Tavendale R, Lang C C, Pearson E R, Colhoun H M, McCarthy M I, Hattersley A T, Morris A D, Palmer C N A

Abstract excerpt

SLCO1B1 gene variants are associated with severe statin-induced myopathy. We examined whether these variants are also associated with general statin intolerance in a large population of patients with type 2 diabetes receiving statins as part of routine clinical care. A total of 4,196 individuals...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 21178985
DOI: 10.1038/clpt.2010.255
PMCID: PMC3353487

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-21178985-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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