Article
RápidoPGS: a rapid polygenic score calculator for summary GWAS data without a test dataset.
Bioinformatics (Oxford, England) - 7 Dec 2021
Reales Guillermo, Vigorito Elena, Kelemen Martin, Wallace Chris
Abstract excerpt
MOTIVATION: Polygenic scores (PGS) aim to genetically predict complex traits at an individual level. PGS are typically trained on genome-wide association summary statistics and require an independent test dataset to tune parameters. More recent methods allow parameters to be tuned on the training data, removing the need for independent test data, but approaches are computationally intensive. Based on fine-mapping...
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