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Computational study to discover potent phytochemical inhibitors against drug target, squalene synthase from Leishmania donovani

31 May 2021

Abstract excerpt

Aims The parasite, Leishmania donovani is responsible for lethal visceral leishmaniasis (VL) in humans. There is a need to investigate novel medicines as antileishmanial drugs, as medication currently introduced for leishmaniasis may cause resistance, serious side-effects, chemical instability and high cost. Therefore, this computational study was designed to explore potential phytochemical inhibitors against...

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PMID: 34141935
DOI: 10.1016/j.heliyon.2021.e07178

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