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Transition From PCR-Ribotyping to Whole Genome Sequencing Based Typing of Clostridioides difficile

1 Jun 2021

Abstract excerpt

Clostridioides difficile causes nosocomial outbreaks which can lead to severe and even life-threatening colitis. Rapid molecular diagnostic tests allow the identification of toxin-producing, potentially hypervirulent strains, which is critical for patient management and infection control. PCR-ribotyping has been used for decades as the reference standard to investigate transmission in suspected outbreaks....

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PMID: 34141631
DOI: 10.3389/fcimb.2021.681518

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