Extended Multilocus Variable-Number Tandem-Repeat Analysis of Clostridium difficile Correlates Exactly with Ribotyping and Enables Identification of Hospital Transmission

Abstract excerpt

PCR ribotyping is currently used in many countries for epidemiological investigation to track transmission and to identify emerging variants of Clostridium difficile. Although PCR ribotyping differentiates over 300 types, it is not always sufficiently discriminatory for epidemiological investigations particularly for common ribotypes, e.g., ribotypes 027, 106, and 017. Multilocus variable-number tandem-repeat...

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