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Article

Pitfalls in HLA Ligandomics—How to Catch a Li(e)gand

1 Jan 2021

Abstract excerpt

Knowledge about the peptide repertoire presented by human leukocyte antigens (HLA) holds the key to unlock target-specific cancer immunotherapies such as adoptive cell therapies or bispecific T cell engaging receptors. Therefore, comprehensive and accurate characterization of HLA peptidomes by mass spectrometry (immunopeptidomics) across tissues and disease states is essential. With growing numbers of...

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Share to Monoclonal and Polyclonal Antibodies Research
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PMID: 34129939
DOI: 10.1016/j.mcpro.2021.100110

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