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Signal pathways of melanoma and targeted therapy

20 Dec 2021

Abstract excerpt

Melanoma is the most lethal skin cancer that originates from the malignant transformation of melanocytes. Although melanoma has long been regarded as a cancerous malignancy with few therapeutic options, increased biological understanding and unprecedented innovations in therapies targeting mutated driver genes and immune checkpoints have substantially improved the prognosis of patients. However, the low response...

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PMID: 34924562
DOI: 10.1038/s41392-021-00827-6

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