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Linking Genetic Diagnosis to Therapeutic Approach in Very Early Onset Inflammatory Bowel Disease: Pharmacologic Considerations.

Paediatric drugs - 1 May 2022

Levine Anne E, Zheng Hengqi B, Suskind David L

Abstract excerpt

Very early onset inflammatory bowel disease (VEO-IBD) is diagnosed in children < 6 years of age, and in rare cases may be due to an identifiable monogenic cause. Recent advances in genetic testing have allowed for more accurate diagnosis, with as many as 100 genes now known to be associated with monogenic inflammatory bowel disease. These genes are involved in many immune pathways and thus may represent potential...

Topics

Age of Onset
Child
Humans
Inflammatory Bowel Diseases
Phenotype

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 35467244
DOI: 10.1007/s40272-022-00503-4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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