Article
High Genotypic Discordance of Concurrent Mycobacterium tuberculosis Isolates from Sputum and Blood of HIV-Infected Individuals.
PloS one - 1 Jan 2015
Ssengooba Willy, Cobelens Frank G, Nakiyingi Lydia, Mboowa Gerald, Armstrong Derek T, Manabe Yukari C, Joloba Moses L, de Jong Bouke C
Abstract excerpt
BACKGROUND: Among HIV-infected individuals with CD4 less than 200 cells/mm3, tuberculosis often has an atypical presentation, is more likely to be disseminated and is diagnostically challenging. We sought to understand the genotypic discordance of concurrent sputum and blood M. tuberculosis (MTB) isolates from HIV-infected individuals. METHODS: From a prospective diagnostic accuracy study with 182 HIV-infected...
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