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Article

Characterization of clonal complexity in tuberculosis by mycobacterial interspersed repetitive unit-variable-number tandem repeat typing.

Journal of clinical microbiology - 1 Nov 2005

García de Viedma Darío, Alonso Rodriguez Noelia, Andrés Sandra, Ruiz Serrano Maria Jesús, Bouza Emilio

Abstract excerpt

In recent years, the application of molecular tools has shown us that clonal complexity in infection by Mycobacterium tuberculosis is not anecdotal. Exogenous reinfections, mixed infections, compartmentalization, and microevolution are different aspects of this issue. The detection and characterization of clonal variants of M. tuberculosis by standard genotyping methods is laborious and frequently requires...

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Identifiers

PMID: 16272501
DOI: 10.1128/JCM.43.11.5660-5664.2005
PMCID: PMC1287844

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