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Article

Circulating miR-34a levels correlate with age-related hearing loss in mice and humans.

Experimental gerontology - 1 Apr 2016

Pang Jiaqi, Xiong Hao, Yang Haidi, Ou Yongkang, Xu Yaodong, Huang Qiuhong, Lai Lan, Chen Suijun, Zhang Zhigang, Cai Yuexin, Zheng Yiqing

Abstract excerpt

Age-related hearing loss (AHL) is a progressive neurodegenerative disease that is largely silent in its initial stages. There is no sensitive blood biomarker for diagnosis or early detection of AHL. MicroRNAs (miRNAs or miRs) are abundant and highly stable in blood, and have been recently described as powerful circulating biomarkers in a wide range of diseases. In the present study, we identified concordant...

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Source

Identifiers

PMID: 26802970
DOI: 10.1016/j.exger.2016.01.009

Genes

SIRT1

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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