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Article

Plasmablasts During Acute Dengue Infection Represent a Small Subset of a Broader Virus-specific Memory B Cell Pool.

EBioMedicine - 1 Oct 2016

Appanna Ramapraba, Kg Srinivasan, Xu Mei Hui, Toh Ying-Xiu, Velumani Sumathy, Carbajo Daniel, Lee Chia Yin, Zuest Roland, Balakrishnan Thavamalar, Xu Weili, Lee Bernett, Poidinger Michael, Zolezzi Francesca, Leo Yee Sin, Thein Tun Linn, Wang Cheng-I, Fink Katja

Abstract excerpt

Dengue is endemic in tropical countries worldwide and the four dengue virus serotypes often co-circulate. Infection with one serotype results in high titers of cross-reactive antibodies produced by plasmablasts, protecting temporarily against all serotypes, but impairing protective immunity in subsequent infections. To understand the development of these plasmablasts, we analyzed virus-specific B cell properties...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 27628668
DOI: 10.1016/j.ebiom.2016.09.003
PMCID: PMC5078588

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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