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Article

Metabolomics reveals microbial-derived metabolites associated with immunoglobulin E responses in filaggrin-related atopic dermatitis.

Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology - 1 Nov 2021

Chiu Chih-Yung, Lin Gigin, Wang Chia-Jung, Hung Shuen-Iu, Chung Wen-Hung

Abstract excerpt

BACKGROUND: Filaggrin (FLG) gene mutation and immunoglobulin E (IgE)-mediated sensitization are the most important predictors of atopic dermatitis (AD). However, a metabolomics-based approach to address the metabolic impact of FLG mutations on allergic IgE responses for AD is still lacking. We, though, determine the relationships of metabolic profiles in AD with FLG mutations and allergic responses. METHODS:...

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Identifiers

PMID: 34087019
DOI: 10.1111/pai.13570

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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