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Article

The levels of amino acid metabolites in serum induce the pathogenesis of atopic dermatitis by mediating the inflammatory protein S100A12.

Scientific reports - 8 Oct 2024

Zhang Yaqi, Xu Heng, Tang Yang, Li Yuhang, Zheng Fengjie

Abstract excerpt

Atopic dermatitis (AD) is a chronic inflammatory skin disease affecting tens of millions of people globally. The causal relationship between metabolites and AD pathology has not yet been formally indicated, and the mediating mechanism by which metabolites affect AD has not yet been explored. This study aimed to determine the genetic relationship between metabolites and AD and to determine the pathways through...

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Identifiers

PMID: 39379513
DOI: 10.1038/s41598-024-74522-1
PMCID: PMC11461510

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