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Article

Apolipoprotein E genotype, lifestyle and coronary artery disease: Gene-environment interaction analyses in the UK Biobank population.

Atherosclerosis - 1 Jul 2021

Bos Maxime M, de Vries Lina, Rensen Patrick Cn, Willems van Dijk Ko, Blauw Gerard Jan, van Heemst Diana, Noordam Raymond

Abstract excerpt

BACKGROUND AND AIMS: The APOE ε4 genotype has a higher risk for developing coronary artery disease (CAD), but there is preliminary evidence that antioxidative lifestyle factors interact with APOE genotype on CAD risk. Here, we assessed the effect modification of physical activity, oily fish and polyunsaturated fatty acid (PUFA) intake with APOE genotype on risk of incident CAD. METHODS: The present study...

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Identifiers

PMID: 34082327
DOI: 10.1016/j.atherosclerosis.2021.05.014

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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