Article
CCN1 gene polymorphisms associated with congenital heart disease susceptibility in Northwest Chinese population from different high-altitude areas.
Environmental science and pollution research international - 1 Oct 2021
Yang Wenke, Bai Jun, Song Xinyu, Zhang Shasha, Chen Nana, You Tao, Yi Kang, Li Zhenglin, Xie Dingxiong, Xie Xiaodong
Abstract excerpt
High-altitude hypoxic environment exposure is considered one of the risk factors for congenital heart disease (CHD), but the genetic factors involved are still unclear. CCN1, one of the synergistic molecules in the hypoxic response, is also an indispensable molecule in cardiac development. Considering that CCN1 may play an important role in the occurrence of CHD in high-altitude areas, we investigated the...
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