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Article

Genome-wide compound heterozygosity analysis highlighted 4 novel susceptibility loci for congenital heart disease in Chinese population.

Clinical genetics - 1 Oct 2018

Jiang T, Huang M, Jiang T, Gu Y, Wang Y, Wu Y, Ma H, Jin G, Dai J, Hu Z

Abstract excerpt

Genome-wide association studies (GWASs) have achieved great success in deciphering the genetic cause of congenital heart disease (CHD). However, the heritability of CHD remains to be clarified, and numerous genetic factors responsible for occurrence of CHD are yet unclear. In this study, we performed a genome-wide search for relaxed forms of compound heterozygosity (CH) in association with CHD using our existing...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 29774522
DOI: 10.1111/cge.13384

Genes

CADM4
LYPD3
UBC

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