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A compendium of Androgen Receptor Variant 7 target genes and their role in Castration Resistant Prostate Cancer

1 Mar 2023

Abstract excerpt

Persistent androgen receptor (AR) signalling is the main driver of prostate cancer (PCa). Truncated isoforms of the AR called androgen receptor variants (AR-Vs) lacking the ligand binding domain often emerge during treatment resistance against AR pathway inhibitors such as Enzalutamide. This review discusses how AR-Vs drive a more aggressive form of PCa through the regulation of some of their target genes...

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Cancer, Lipids, and Metabolism
Hormonal and reproductive studies
Prostate Cancer Treatment and Research

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 36937454
DOI: 10.3389/fonc.2023.1129140

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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