Identification of Viral Variants from Functional Genomics Data.

Abstract excerpt

Background: Virus mutants are commonly used for studying the role of individual viral proteins in infections and are increasingly investigated with functional genomics experiments of infected cells that use sequencing-based assays such as RNA-seq or ATAC-seq. However, existing mutant virus strains are often poorly documented, in particular if they have been created decades ago. Identifying viral variants directly...

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