Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Expression of Mismatch Repair Proteins in Merkel Cell Carcinoma

21 May 2021

Abstract excerpt

We aimed to assess for the first time the mismatch repair (MMR) protein expression in Merkel cell carcinoma (MCC). Immunohistochemistry was performed for MLH1, MSH2, MSH6, and PMS2 on patients’ tumor tissue (n = 56), including neighbored healthy control tissue. In cases with low-level MMR expression (<10th percentile), we performed multiplex PCR in combination with high-resolution capillary electrophoresis in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Plant Disease Resistance and Genetics
Share to Polyomavirus and related diseases
Share to Tumors and Oncological Cases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 34063983
DOI: 10.3390/cancers13112524

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Expression of Mismatch Repair Proteins in Merkel Cell CarcinomaPMID 34063983Read ↗

Aberrant expression of ALK and EZH2 in Merkel cell carcinomaSemantic proximity Read ↗

Investigation of mRNA expression levels of DNA damage response genes in Merkel Cell Polyomavirus-positive Merkel Cell Carcinoma: a pilot studySemantic proximity Read ↗

Characterizing DNA methylation signatures and their potential functional roles in Merkel cell carcinomaSemantic proximity Read ↗

DNA Damage Stress Control Is a Truncated Large T Antigen and Euchromatic Histone Lysine Methyltransferase 2–Dependent Central Feature of Merkel Cell CarcinomaSemantic proximity Read ↗

DNA Mismatch Repair Deficiency in Breast CarcinomaSemantic proximity Read ↗

RB1gene in Merkel cell carcinoma: hypermethylation in all tumors and concurrent heterozygous deletions in the polyomavirus-negative subgroupSemantic proximity Read ↗

No Evidence of Microsatellite Instability and Loss of Mismatch-Repair-Protein Expression in Squamous Cell Carcinoma of the PenisSemantic proximity Read ↗

The Relationship Between Mismatch Repair Deficiency and PD-L1 Expression in Breast Carcinoma.Semantic proximity Read ↗

Mismatch Repair Protein Loss as a Prognostic and Predictive Biomarker in Breast Cancers Regardless of Microsatellite InstabilitySemantic proximity Read ↗

Mismatch Repair Deficiency and Microsatellite Instability in Triple-Negative Breast Cancer: A Retrospective Study of 440 PatientsSemantic proximity Read ↗

Simple IHC reveals complex MMR alternations than PCR assays: Validation by LCM and next‐generation sequencingSemantic proximity Read ↗

The Etiology and Epidemiology of Merkel Cell CarcinomaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.