Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mitochondrial Dysfunction in Podocytes Caused by CRIF1 Deficiency Leads to Progressive Albuminuria and Glomerular Sclerosis in Mice

2 May 2021

Abstract excerpt

Recent studies have implicated mitochondrial disruption in podocyte dysfunction, which is a characteristic feature of primary and diabetic glomerular diseases. However, the mechanisms by which primary mitochondrial dysfunction in podocytes affects glomerular renal diseases are currently unknown. To investigate the role of mitochondrial oxidative phosphorylation (OxPhos) in podocyte dysfunction, glomerular...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chronic Kidney Disease and Diabetes
Share to Genetic and Kidney Cyst Diseases
Share to Renal Diseases and Glomerulopathies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 34063207
DOI: 10.3390/ijms22094827

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mitochondrial Dysfunction in Podocytes Caused by CRIF1 Deficiency Leads to Progressive Albuminuria and Glomerular Sclerosis in MicePMID 34063207Read ↗

Disruption of CR6-interacting factor-1 (CRIF1) in mouse islet beta cells leads to mitochondrial diabetes with progressive beta cell failure.Semantic proximity Read ↗

Deficiency in Apoptosis-Inducing Factor Recapitulates Chronic Kidney Disease via Aberrant Mitochondrial Homeostasis.Semantic proximity Read ↗

Krüppel-like factor 6 regulates mitochondrial function in the kidneySemantic proximity Read ↗

CPT1α maintains phenotype of tubules via mitochondrial respiration during kidney injury and repair.Semantic proximity Read ↗

NDUFS4 Regulates Cristae Remodeling in Diabetic Kidney DiseaseSemantic proximity Read ↗

<i>Opa1</i> overexpression protects from early onset <i>Mpv17</i> <sup> <i>-/-</i> </sup> -related mouse kidney diseaseSemantic proximity Read ↗

IHG-1 Promotes Mitochondrial Biogenesis by Stabilizing PGC-1αSemantic proximity Read ↗

PGC-1α overexpression protects against aldosterone-induced podocyte depletion: role of mitochondriaSemantic proximity Read ↗

Increased mitochondrial fragmentation in polycystic kidney disease acts as a modifier of disease progressionSemantic proximity Read ↗

Loss of MTX2 causes mitochondrial dysfunction, podocyte injury, nephrotic proteinuria and glomerulopathy in mice and patientsSemantic proximity Read ↗

Amelioration of progressive renal injury by genetic manipulation of <i>Klotho</i> geneSemantic proximity Read ↗

Primary coenzyme Q deficiency in Pdss2 mutant mice causes isolated renal disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.