Article
Allogeneic stem cell transplantation for AML patients with RUNX1 mutation in first complete remission: a study on behalf of the acute leukemia working party of the EBMT.
Bone marrow transplantation - 1 Oct 2021
Waidhauser Johanna, Labopin Myriam, Esteve Jordi, Kröger Nicolaus, Cornelissen Jan, Gedde-Dahl Tobias, Van Gorkom Gwendolyn, Finke Jürgen, Rovira Montserrat, Schaap Nicolaas, Petersen Eefke, Beelen Dietrich, Bunjes Donald, Savani Bipin, Schmid Christoph, Nagler Arnon, Mohty Mohamad
Abstract excerpt
Acute myeloid leukemia with runt-related transcription factor 1 gene mutation (RUNX1+ AML) is associated with inferior response rates and outcome after conventional chemotherapy. We performed a retrospective, registry-based analysis to elucidate the prognostic value of RUNX1 mutation after allogeneic stem cell transplantation (alloSCT). All consecutive adults undergoing alloSCT for AML in first complete remission...
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