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Autophagy in Stem Cell Biology: A Perspective on Stem Cell Self-Renewal and Differentiation

1 Jan 2018

Abstract excerpt

Autophagy is a highly conserved cellular process that degrades modified, surplus, or harmful cytoplasmic components by sequestering them in autophagosomes which then fuses with the lysosome for degradation. As a major intracellular degradation and recycling pathway, autophagy is crucial for maintaining cellular homeostasis, as well as for remodeling during normal development. Impairment of this process has been...

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PMID: 29765428
DOI: 10.1155/2018/9131397

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