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Autophagy in stem cells: repair, remodelling and metabolic reprogramming

15 Feb 2018

Abstract excerpt

Autophagy is a catabolic pathway by which cellular components are delivered to the lysosome for degradation and recycling. Autophagy serves as a crucial intracellular quality control and repair mechanism but is also involved in cell remodelling during development and cell differentiation. In addition, mitophagy, the process by which damaged mitochondria undergo autophagy, has emerged as key regulator of cell...

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PMID: 29483129
DOI: 10.1242/dev.146506

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