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Article

Engraftment of Human Hematopoietic Cells in Biomaterials Implanted in Immunodeficient Mouse Models.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2021

Mian Syed A, Bonnet Dominique

Abstract excerpt

Over the last 20 years, significant progress has been made in the development of immunodeficient mouse models that now represents the gold standard tool in stem cell biology research. The latest major improvement has been the use of biomaterials in these xenogeneic mouse models to generate human "bone marrow like" tissues, which not only provides a more relevant xenograft model but can also potentially enable us...

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PMID: 34057727
DOI: 10.1007/978-1-0716-1425-9_18

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