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Article

Autophagy and ALS: mechanistic insights and therapeutic implications

31 May 2021

Abstract excerpt

: ALS: amyotrophic lateral sclerosis; Atg: autophagy-related; CHMP2B: charged multivesicular body protein 2B; DPR: dipeptide repeat; FTD: frontotemporal dementia; iPSC: induced pluripotent stem cell; LIR: LC3-interacting region; MAP1LC3/LC3: microtubule associated protein 1 light chain 3; MTOR: mechanistic target of rapamycin kinase; PINK1: PTEN induced kinase 1; RNP: ribonuclear protein; sALS: sporadic ALS;...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 34057020
DOI: 10.1080/15548627.2021.1926656

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