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Cellular and molecular mechanisms in graft-versus-host disease

7 Dec 2015

Abstract excerpt

Graft-versus-host disease is a complication in patients undergoing hematopoietic stem cell transplantation. Graft-versus-host disease includes acute graft-versus-host disease and chronic graft-versus-host disease. Host APCs (e.g., dendritic cells and macrophages), effector T cells (e.g., Th1, Th17, and abnormal Th17:regulatory T cell ratio), B cells, and NK cells are implicated in graft-versus-host disease...

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PMID: 26643713
DOI: 10.1189/jlb.4ru0615-254rr

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