Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Analysis of 200 000 exome-sequenced UK Biobank subjects fails to identify genes influencing probability of developing a mood disorder resulting in psychiatric referral.

Psychiatric genetics - 1 Oct 2021

Curtis David

Abstract excerpt

BACKGROUND: Depression is moderately heritable but there is no common genetic variant which has a major effect on susceptibility. A previous analysis of 50 000 exome-sequenced subjects failed to implicate any genes or sets of genes in which rare variants were associated with risk of affective disorder requiring specialist treatment. A much larger exome-sequenced dataset is now available. METHODS: Data from...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biological Specimen Banks
Share to Exome
Share to Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mood Disorders

Share to Probability

Share to Referral and Consultation

Share to United Kingdom

Source

Identifiers

PMID: 34050118
DOI: 10.1097/YPG.0000000000000282

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Analysis of 200 000 exome-sequenced UK Biobank subjects fails to identify genes influencing probability of developing a mood disorder resulting in psychiatric referral.PMID 34050118Read ↗

Analysis of 50,000 exome-sequenced UK Biobank subjects fails to identify genes influencing probability of developing a mood disorder resulting in psychiatric referral.Semantic proximity Read ↗

Analysis of 50,000 exome-sequenced UK Biobank subjects fails to identify genes influencing probability of psychiatric referralSemantic proximity Read ↗

Analysis of 470,000 exome-sequenced cases and controls fails to identify any genes impacting risk of developing affective disorder.Semantic proximity Read ↗

Whole-exome sequencing in UK Biobank reveals rare genetic architecture for depression.Semantic proximity Read ↗

The genetics of the mood disorder spectrum: genome-wide association analyses of over 185,000 cases and 439,000 controlsSemantic proximity Read ↗

Exome-wide screening identifies novel rare risk variants for major depression disorder.Semantic proximity Read ↗

The Genetics of the Mood Disorder Spectrum: Genome-wide Association Analyses of More Than 185,000 Cases and 439,000 ControlsSemantic proximity Read ↗

Prevalence and characteristics of probable major depression and bipolar disorder within UK biobank: cross-sectional study of 172,751 participants.Semantic proximity Read ↗

Whole exome sequencing in the UK Biobank reveals risk gene<i>SLC2A1</i>and biological insights for major depressive disorderSemantic proximity Read ↗

Multiple measures of depression to enhance validity of Major Depressive Disorder in the UK BiobankSemantic proximity Read ↗

Polygenic burden could explain high rates of affective disorders in a community with restricted founder population.Semantic proximity Read ↗

Association between major depressive disorder and multiple disease outcomes: a phenome-wide Mendelian randomisation study in the UK BiobankSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.