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Analysis of 50,000 exome-sequenced UK Biobank subjects fails to identify genes influencing probability of developing a mood disorder resulting in psychiatric referral.

Journal of affective disorders - 15 Feb 2021

Curtis David

Abstract excerpt

BACKGROUND: Depression is moderately heritable but there is no common genetic variant which has a major effect on susceptibility. It is possible that some very rare variants could have substantial effect sizes and these could be identified from exome sequence data. METHODS: Data from 50,000 exome-sequenced UK Biobank participants was analysed. Subjects were treated as cases if they had reported having seen a...

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PMID: 33333475
DOI: 10.1016/j.jad.2020.12.025

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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