Article

A multimodal atlas of COVID-19 severity identifies hallmarks of dysregulated immunity

2025-09-21

Abstract excerpt

The alpha-variant wave of the COVID-19 pandemic provided a unique opportunity to study, at single-cell resolution, how near-universal exposure to the same pathogen can lead to either effective or dysfunctional immune responses in humans. Although single-cell RNA-sequencing studies have characterized immune cellular features of COVID-19, they have not shown how tocilizumab treatment changes these features at single...

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Literature Corpus work: bba4510b-0e15-5679-bcbb-d02181bdc6bb
DOI: 10.1101/2025.09.19.25334095

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