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Vitamin D stimulates miR-26b-5p to inhibit placental COX-2 expression in preeclampsia

27 May 2021

Abstract excerpt

Abstract Vitamin D insufficiency or deficiency during pregnancy has been associated with an increased risk of preeclampsia. Increased placental cyclooxygenase-2 (COX-2) activity was proposed to contribute to the inflammatory response in preeclampsia. This study was to investigate if vitamin D can benefit preeclampsia by inhibiting placental COX-2 expression. Placenta tissues were obtained from 40 pregnant women...

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PMID: 34045549
DOI: 10.1038/s41598-021-90605-9

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