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Article

Complexity of <i>COX</i>-<i>2</i> gene regulation

21 May 2008

Abstract excerpt

Overexpression of the enzyme COX-2 (cyclo-oxygenase-2) is associated with various pathophysiological conditions, including inflammatory diseases and different cancers. Increased synthesis of COX-2 in fetal membranes and the myometrium is also linked with the onset of term and preterm labour. COX-2 gene regulation is controlled at various levels including gene transcription and post-transcriptional events. The...

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PMID: 18482003
DOI: 10.1042/bst0360543

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