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The accumulation of exosome-associated microRNA-1246 and microRNA-150-3p in human red blood cell suspensions

27 May 2021

Abstract excerpt

BACKGROUND: Transfusion-related immunomodulation (TRIM) can be caused by exosomes, in which case, microRNAs (miRNAs) are one critical factor impacting exosome behavior. This study aims to investigate and analyze the expression profiles of exosomal miRNA in red blood cell (RBC) suspensions during storage and to identify potential TRIM-related miRNAs as well as their potential functions. METHODS: A total of 25...

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PMID: 34044888
DOI: 10.1186/s12967-021-02887-2

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