Article
Intercellular transport of microRNAs.
Arteriosclerosis, thrombosis, and vascular biology - 1 Feb 2013
Boon Reinier A, Vickers Kasey C
Abstract excerpt
Extracellular microRNAs (miRNA) are present in most biological fluids, relatively stable, and hold great potential for disease biomarkers and novel therapeutics. Circulating miRNAs are transported by membrane-derived vesicles (exosomes and microparticles), lipoproteins, and other ribonucleoprotein complexes. Evidence suggests that miRNAs are selectively exported from cells with distinct signatures that have been...
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