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Differential profiling of human red blood cells during storage for 52 selected microRNAs

11 Feb 2010

Abstract excerpt

BACKGROUND: MicroRNAs (miRNAs), the negative regulators of cellular mRNAs, are present in mature red blood cells (RBCs) in abundance relative to other blood cells. So far, there are no studies aimed at identifying large-scale miRNA profiles during storage of RBCs. STUDY DESIGN AND METHODS: RNA samples from each RBC bag stored at 4 degrees C were collected on Days 0, 20, and 40 and subjected to miRNA profiling by...

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PMID: 20158686
DOI: 10.1111/j.1537-2995.2010.02585.x

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