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Article

Disruption of microtubule function in cultured human cells by a cytotoxic ruthenium( ii ) polypyridyl complex

18 Nov 2019

Abstract excerpt

Treatment of cultured human cell lines with a cytotoxic IC 50 dose of ∼2 μM tris(diphenylphenanthroline)ruthenium( ii ) chloride ( RPC2 ) retards or arrests microtubule motion as tracked by visualizing fluorescently-tagged microtubule plus end-tracking proteins.

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Identifiers

PMID: 34040721
DOI: 10.1039/c9sc05671h

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