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Article

Comprehensive Genomic Profiling of EBV-Positive Diffuse Large B-cell Lymphoma and the Expression and Clinicopathological Correlations of Some Related Genes

25 Jul 2019

Abstract excerpt

Epstein–Barr virus (EBV)-positive diffuse large B-cell lymphoma (EBV+ DLBCL) is a rare type of lymphoma with a high incidence in elderly patients, poor drug response and unfavorable prognosis. Despite advances in genomic profiling and precision medicine in DLBCL, EBV+ DLBCL remain poorly characterized and understood. We detected 9 EBV+ and 6 EBV negative cases for next-generation sequencing (NGS) and then...

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PMID: 31403034
DOI: 10.3389/fonc.2019.00683

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