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Article

Inhibition of the RBMS1/PRNP axis improves ferroptosis resistance‐mediated oxaliplatin chemoresistance in colorectal cancer

20 Oct 2023

Abstract excerpt

The majority of patients with advanced colorectal cancer have chemoresistance to oxaliplatin, and studies on oxaliplatin resistance are limited. Our research showed that RNA-binding motif single-stranded interacting protein 1 (RBMS1) caused ferroptosis resistance in tumor cells, leading to oxaliplatin resistance. We employed bioinformatics to evaluate publically accessible data sets and discovered that RBMS1 was...

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PMID: 37861356
DOI: 10.1002/mc.23647

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